Attachment

Second NHP Study Results -- Preliminary - 1 Three arm, vehicle controlled study administering favipiravir twice a day 250 mg/kg favipiravir BID on Day 0, maintenance dose regimen of 150 mg/kg BID on Days 1-13. 125 mg BID on Day 0 followed by 75 mg BID on Days 113 (expected similar exposure to influenza regimen) EBOV challenge the day favipiravir started Favipiravir administered BID by oral gavage Animals sedated twice a day Confidential