A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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March 14, 2021 - Global - 119,200,000/2,600,000; USA - 29,200,000/531,800 300,000/532,400 New Daily Confirmed COVID-19 Cases In the U.S. a0 a PIE LE anit THe brit aft TET bet at ont feREe ETRT GET TET STALL B/TT TEAIT ine One Ele Ene ELE fa ogre Bit fated St Ea Tes prs ao bea ys ons as Gly zi ons tre SWE 2020/2021 PRESS: NBC "Meet the Press" with Chuck Todd; CNN State of the Union" with Jake Tapper; Fox News with Chris Wallace; Gray TV "Full Court Press" with Greta Van Susteren
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March 15, 2021 - Global - 119,600,000/2,600,000; USA -29,300,000/532,400 Got call tonight from Larry Horowitz saying that Drew Weissman and his collaborator are planning to hold a press conference to discuss their studies in mice showing that an intramuscular injection of the mRNA vaccine leads to an immune response in the amniotic fluid of the pups in a pregnancy model. The FDA has already received the DART (Development and Reproductive Toxicology) studies from Moderna and Pfizer. According to Emily these studies were clean. The FDA has heard about the Weissman studies and feels that they are invalid. The two companies also feel that the studies are invalid. However, we cannot blow them off for obvious reasons. Even if the Weissman studies prove to be invalid, the fact that they are holding a press conference is going to create a huge mess. Hopefully, we can get this sorted out and have a repeat of studies to counter this finding. More later. Jeff Zients has heard about this and called me tonight at 9:30 PM. I told him we have to get the FDA out their showing that they have DART studies and explaining what their studies showed. Cases coming down: Yet Europe is seeing an upswing of cases resulting mostly from B.1.1.1.7: '9,300,000/533,100 Today I received on a virtual zoom the Ivan Alan Award for Social Courage given by Georgia Tech University and it's President doctor Angel Cabrera. There was a video about my accomplishments and Rochelle Walensky joined us to celebrate the award. Rochelle was very generous in calling me her hero, her mentor, and her friend. I should point out at this point that Rochelle has become closer and closer to me in our very collegial relationship. In addition, I should point out that I have been getting a number of awards and prizes that I had not even documented in these notes. It is a shame that things are moving so quickly that I don't even have time to savor for a moment the many awards that I have been getting. PRESS: Did White House Press briefing today with Rochelle and Andy;
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March 16, 2021 - Global - 120,000,000/2,700,000; USA - 29,300,000/533,100 I took the led in pushing Janet Woodcock (FDA) and Rochelle Walensky (CDC) to make sure that all their ducks were in order. In fact, Janet checked and both Pfizer and Moderna had clean DART studies on record and CDC was following closely 2000 vaccinated pregnant women from a cohort of 31,000 and no red flags. All good so far. Participated in a very nice function at the National Cathedral where Francis Collins and I and Eliseo Perez-Stable gave brief remarks to various ministers from surrounding counties such as Montgomery, Arlington, Fairfax, District of Columbia, and others. The purpose was to have these African American pastors get publicly vaccinated in the cathedral so that their constituents would follow. It was one of many outreach efforts that Francis and I and others have been doing over the past months to stimulate interest in getting vaccinated. Summary of vaccines below: Company Platform Non-clinical results #who got Protection from Protection from Efficacy against vaccine hospitalization COVIDseveredz --_--milder COVID from COVID-19 (some at home) mRNA-1273 Neutralizing Abs; Strong 97% (1 in vaccine I 97% (30 cases in MRNA in lipid Thi CD4+, CD8+; arm after 2nd --_| placebo arm; 0 in MOderNd panoparticle protection from dose vaccine reported but challenge (macaques) hospitalized) 1 severe per FDA) BNT162b2 I Neutralizing Abs; Strong I~18,600 I 100% 100% (9 cases in I 95% MRNA in lipid Tht CD4+, CD8+; placebo arm; 0 in nanoparticle protection from vaccine- 1 initially challenge (macaques) severe but not) JNJ-78436725 I Neutralizing Abs; Strong I~22,000 I 100% 85.4% across 3 sites I 72% US; 61% Non-replicating Thi CD4+>Th2; CD8+; I US, Latin (7 deaths, 16 Latin America; human challenge protection _| America, hospitalizations, all I 65% S. Africa adenovirus/ONA (macaque) S.Africa in placebo arm) (96% 81.351) 'AZO 1222 I Neutralizing Abs; Strong I ~8588 100% 100% (15 in placebo I 70% overall; % Non-replicating Thi CD4+ > Th2; CD8+; = all hospitalized; 0 I 76% 1 dose; s. Astrazeneca I Chimp Adenovirus- protection from in vaccine) Africa trial DNA challenge (macaques) halted for mild NVX-CoVv2373 I Neutralizing Abs; Strong I ~8833 100% 100% (10 severe in I 96.4% UK]89% NOVAVAX spike protein/RBD + Thi CD4 > Th2; challenge I (Phase 3 placebo in UK/SA; 0 I B117 UK; 55% Matrix M adjuvant protection (macaques) _| UK; 2b SA) in vaccine) 'SA (94% 81351) Sputnik y I A@26and ads I NAbs;IFN-ysecretion I~14964 -- I 100% 100% (20 in placebo; I 91.6% adenovirus/ONA PMBCS, cellular response vaccine) '9,400,000/534, '9,400,000/535,200 1d PRESS: MSNBC "Morning Joe" with Joe Scarborough; ABC "GMA3" with Jen Ashton; Wall Street Journal - CEO Council with John Bussey; Podcast with The Economist; National Cathedral Function with Press
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March 17, 2021 - Global - 120,400,000/2,700,000; USA - 29,400,000/534,100 Testified before the House Energy and Commerce Oversight & Investigations Subcommittee chaired by Diana De Gette (D-CO) with ranking member Morgan Griffith (R- VA). Good hearing with the usual snarkiness from David McKinley (R-WV) and Gary Palmer (R-AL). Several question centered around the GOP angry because the Dems are not giving Trump enough credit for the vaccine. It is reflecting what Trump has been saying to the media. Pres. Joe Biden sent me a thank you letter: Letter from president Joe Biden PRESS: NBC Late Show with Seth Meyers; White House Press Conference
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2021-03-18 00:00
Anthony S. Fauci
March 18, 2021 - Global - 120,900,000/2,700,000; USA - 29,400,000/535,200 Testified before the Senate HELP Committee chaired by Sen. Patty Murray (D_WA) and ranking Minority Richard Burr (R-NC). I had my typical fight with Sen. Rand Paul who insisted that masks were pure theater. I blew him away. After the Hearing, I briefed the POTUS and VPOTUS on Building Vaccine Confidence. Present virtually - me, Andy Slavitt, Marcella Nunez-Smith, and Courtney Rowe. In the Oval - Jeff, Natalie Quillian, Anita Dunn. Had call with Jeff, David K. Natalie, Anne Schuchat regarding alarming increase in NYC of B.1.526. Anne will call Zucker to suggest strongly to shut down bars and restaurants. We are afraid of a surge that we had expected since NYC tends to follow Europe, which is surging now following a plateau. SA giving vaccine to Canada and Mexico. For Mexico it is a quid pro quo to control immigration at the border. Also, AstraZeneca continues to mess up on their examination of data with the DSMB. They have shown extreme incompetence throughout this entire affair with mixing up clinical trial data in the UK to not having equity demographically in their USA trial USA Global New Daily Confirmed COVID-19 Cases In the U.S. a0 & B PIE oye c)-) E2']-) Blil Pata AES Te brs iff TES bes iys os eS snr ol mir ET one mere SWE 2020/2021 9,600,000/538,300 i} ' PRESS: NBC "Today" with Savannah Guthrie; Did short TV hots with local stations in Alabama, Louisiana; North Carolina; South Carolina; CNN with Chris Cuomo
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Mar 18, 2021 Source: Johns Hopkins University CSSE COVID-19 Data CC BY '9,700,000/540,000
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March 19, 2021 - Global USA Still flattening. General worry about surge while several states are pulling back on mask mandates and other public health measures: PRESS: CBS "This Morning" with Gayle King; Snapchats with White House Comms; MSNBC "All In" with Chris Hayes
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March 20, 2021 - Global - 122,000,000/2,700,000; USA - 29,600,000/538,300 Had our newly established Saturday AM meeting with the medical team led by Jeff Zients to go over important issues. I brought up for the first time the issue of having Biden lead an effort to allow LMICs to produce their own vaccine. This could be a legacy issue for him similar to what George WQ. Buch did with PEPFAR. Cases starting to come up after the plateau: New Daily Confirmed COVID-19 Cases In the U.S. a0 6L,8 PTE fe BEE Tez pre itt TEL bryt fy oye eeeet oriet ELE clad Beyer eaiad STE AyLT TALL sz/O0 T/T THO PAL ozs EWS ORs Bae aye we a8 one oie eye fe ans THe PTs iff PES is os oer Bie zie ab ane mere SWE fg 3g & °° 2020/2021 -- Global USA PRESS: NBC "Today Weekend" with Kristen Welker and Peter Alexander;
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Mar 20, 2021 While Europe continues to surge: And Brazil follows: Daily new confirmed COVID-19 deaths per million people Our World Shown is the rolling 7-day average, Limited testing and challenges in the attribution of the cause of death means that the number of confirmed deaths may not be an accurate count of the true number of deaths from COVID-19. in Data Brazil L\ Chile ---- Paraguay ga FES HoT Eat «----* Mexico ~ _.~ ==. ee ---- Argentina SS -------- -- _s Colombia ;-- Ecuador = Bolivia ---- A 3 Si __, .--- World ae ue Guyana ig = Venezuela --. =e --"S, __ Suriname