A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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March 10, 2021 - Global - 117,300-,000/2,600,000; USA - 29,000,000/526,200 Had a very moving tribute to me upon the receipt of the Yale University School of Management "Legend in Leadership" Award from the Chief Executive Leadership Institute. Moving comments by Albert Bourla (Pfizer), Alex Gorsky (J & J). PRESS: CNN "New Day" with John Berman; Interview with Carolyn Johnson of the Washington Post; Instagram with Eugenio Derbez (Mexican-American entertainer) Historical comparison of the vaccine efforts of Trump versus Biden in NY Times article by Sharon La Franiere: ,100,000/527,700 Biden Got the Vaccine Rollout Humming, With Trump's Help Trump administration officials grumble that they laid the groundwork for surging vaccinations, but some hard work in the trenches has helped pick up the pace of production. See link below: https://www.nytimes.com/2021/03/10/us/politics/biden-coronavirus-vaccine.html
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March 11, 2021 - Global -117,800/2,600,000; USA - 29,100,000/527,700 Had Zoom with Jeff and the team to go over the POTUS speech for tonight to commemorate the 1 year anniversary from the time (March 11, 2020) when the WHO declared this a pandemic of global health concern and we shut down travel from Europe. This was a big day for me 1 year ago - (go back to notes of March 11, 2020). Also, I have been pushing with Jeff and Rochelle to have the CDC be a bit less "risk averse" in their recommendations of what a person can do USA Global - New Daily Confirmed COVID-19 Cases In the U.S. a0 a4 Lfe Ehard THz biz it TEE bey Eve Oe iT {280 OzEC ELT BEsLT para STL BITE THLE gzot TTS nts Oni ETS Des Eve oye Fa.) Elsa Bite zt at Eta) Te Sete our miir GzyE Eta SWE 2020/2021 once they are fully vaccinated. The CDC really needs to step up and give recommendations for travel, workplace, houses of worship. They are dragging their feet. I am gently coaching Rochelle to go by her own instincts and not always yielding to the rigidity of the career CDC staff. • Had Zoom call with Gov. Dan McKee of Rhode Island asking advice about the next few weeks and his plans for the state PRESS: NBC "This Morning" with Savannah Guthrie; ABC "Good Morning America" with George Stephanopoulos; ESPN "First Take" TV with Max Kellerman, Stephen A. Smith, and Molly Qerim Rose (discussed my 5 favorite athletes); Podcast ("We Can Do This") with Robin Roberts; CBS Evening News with Norah O'Donnell; Filmed Stephen Colbert for tomorrow night; MSNBC - Rachel Maddow
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Mar 11, 2021
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March 12, 2021 - Global - USA Still plateauing: Briefed the Principals for our weekly briefing. I showed the replication cycle of SARS-CoV-2 and the vulnerable targets for direct anti-viral therapy David Kessler together with Rick Levin (formerly of Yale) made a proposal to provide through the congress 5 billion to me and NIAID to decide how we wanted to put together a "vaccine manufacturing plan that would involve everything from the fundamental research going into pandemic preparedness to the actual manufacturing of 300,000,000 doses of vaccine per year. .200,000/530,700 '9,200,000/53 1,800 New Daily Confirmed COVID-19 Cases In the U.S. Confirmed Canes (Thousards| a0 Bi aya as ayflz ayo a2 of Sia svi? S24 Sai ea Gal ei28 r= Wiz Wi Ty26 Bfe ary efia ayaa oN la gyao ST TLL Tay LB Li? qa afi? WaL air ziLa WoL ay28 ay This is an extraordinary offer then I will have to sit down with my team particularly John Mascola who was on the call with us to determine what aspect of this multifaceted plan that David proposed would be owned by us here at NIAID versus what we would give to HHS/ASPR/BARDA. I asked John to think about a team that we could put together in the beginning of the week to come back to David with a plan. Obviously, we will have to go 2 Francis Collins and thoroughly briefed him and get his buy in. PRESS: Zoom interview with Spike Lee for a documentary that he is filming; Politico by Sarah Owermohle and Erin Banco Fauci takes on a new role: Biden's Covid whisperer Few others cast as long a shadow as Fauci -- who over the last year has given America a crash course in epidemiology -- especially with top health posts vacant.
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2021-03-13 00:00
Anthony S. Fauci
March 13, 2021 Global - 118,800,000/2,600,000; USA - 29,200,000/530,700 PRESS: Filmed with Mark Manucci for PBS
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March 14, 2021 - Global - 119,200,000/2,600,000; USA - 29,200,000/531,800 300,000/532,400 New Daily Confirmed COVID-19 Cases In the U.S. a0 a PIE LE anit THe brit aft TET bet at ont feREe ETRT GET TET STALL B/TT TEAIT ine One Ele Ene ELE fa ogre Bit fated St Ea Tes prs ao bea ys ons as Gly zi ons tre SWE 2020/2021 PRESS: NBC "Meet the Press" with Chuck Todd; CNN State of the Union" with Jake Tapper; Fox News with Chris Wallace; Gray TV "Full Court Press" with Greta Van Susteren
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March 15, 2021 - Global - 119,600,000/2,600,000; USA -29,300,000/532,400 Got call tonight from Larry Horowitz saying that Drew Weissman and his collaborator are planning to hold a press conference to discuss their studies in mice showing that an intramuscular injection of the mRNA vaccine leads to an immune response in the amniotic fluid of the pups in a pregnancy model. The FDA has already received the DART (Development and Reproductive Toxicology) studies from Moderna and Pfizer. According to Emily these studies were clean. The FDA has heard about the Weissman studies and feels that they are invalid. The two companies also feel that the studies are invalid. However, we cannot blow them off for obvious reasons. Even if the Weissman studies prove to be invalid, the fact that they are holding a press conference is going to create a huge mess. Hopefully, we can get this sorted out and have a repeat of studies to counter this finding. More later. Jeff Zients has heard about this and called me tonight at 9:30 PM. I told him we have to get the FDA out their showing that they have DART studies and explaining what their studies showed. Cases coming down: Yet Europe is seeing an upswing of cases resulting mostly from B.1.1.1.7: '9,300,000/533,100 Today I received on a virtual zoom the Ivan Alan Award for Social Courage given by Georgia Tech University and it's President doctor Angel Cabrera. There was a video about my accomplishments and Rochelle Walensky joined us to celebrate the award. Rochelle was very generous in calling me her hero, her mentor, and her friend. I should point out at this point that Rochelle has become closer and closer to me in our very collegial relationship. In addition, I should point out that I have been getting a number of awards and prizes that I had not even documented in these notes. It is a shame that things are moving so quickly that I don't even have time to savor for a moment the many awards that I have been getting. PRESS: Did White House Press briefing today with Rochelle and Andy;
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March 16, 2021 - Global - 120,000,000/2,700,000; USA - 29,300,000/533,100 I took the led in pushing Janet Woodcock (FDA) and Rochelle Walensky (CDC) to make sure that all their ducks were in order. In fact, Janet checked and both Pfizer and Moderna had clean DART studies on record and CDC was following closely 2000 vaccinated pregnant women from a cohort of 31,000 and no red flags. All good so far. Participated in a very nice function at the National Cathedral where Francis Collins and I and Eliseo Perez-Stable gave brief remarks to various ministers from surrounding counties such as Montgomery, Arlington, Fairfax, District of Columbia, and others. The purpose was to have these African American pastors get publicly vaccinated in the cathedral so that their constituents would follow. It was one of many outreach efforts that Francis and I and others have been doing over the past months to stimulate interest in getting vaccinated. Summary of vaccines below: Company Platform Non-clinical results #who got Protection from Protection from Efficacy against vaccine hospitalization COVIDseveredz --_--milder COVID from COVID-19 (some at home) mRNA-1273 Neutralizing Abs; Strong 97% (1 in vaccine I 97% (30 cases in MRNA in lipid Thi CD4+, CD8+; arm after 2nd --_| placebo arm; 0 in MOderNd panoparticle protection from dose vaccine reported but challenge (macaques) hospitalized) 1 severe per FDA) BNT162b2 I Neutralizing Abs; Strong I~18,600 I 100% 100% (9 cases in I 95% MRNA in lipid Tht CD4+, CD8+; placebo arm; 0 in nanoparticle protection from vaccine- 1 initially challenge (macaques) severe but not) JNJ-78436725 I Neutralizing Abs; Strong I~22,000 I 100% 85.4% across 3 sites I 72% US; 61% Non-replicating Thi CD4+>Th2; CD8+; I US, Latin (7 deaths, 16 Latin America; human challenge protection _| America, hospitalizations, all I 65% S. Africa adenovirus/ONA (macaque) S.Africa in placebo arm) (96% 81.351) 'AZO 1222 I Neutralizing Abs; Strong I ~8588 100% 100% (15 in placebo I 70% overall; % Non-replicating Thi CD4+ > Th2; CD8+; = all hospitalized; 0 I 76% 1 dose; s. Astrazeneca I Chimp Adenovirus- protection from in vaccine) Africa trial DNA challenge (macaques) halted for mild NVX-CoVv2373 I Neutralizing Abs; Strong I ~8833 100% 100% (10 severe in I 96.4% UK]89% NOVAVAX spike protein/RBD + Thi CD4 > Th2; challenge I (Phase 3 placebo in UK/SA; 0 I B117 UK; 55% Matrix M adjuvant protection (macaques) _| UK; 2b SA) in vaccine) 'SA (94% 81351) Sputnik y I A@26and ads I NAbs;IFN-ysecretion I~14964 -- I 100% 100% (20 in placebo; I 91.6% adenovirus/ONA PMBCS, cellular response vaccine) '9,400,000/534, '9,400,000/535,200 1d PRESS: MSNBC "Morning Joe" with Joe Scarborough; ABC "GMA3" with Jen Ashton; Wall Street Journal - CEO Council with John Bussey; Podcast with The Economist; National Cathedral Function with Press
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March 17, 2021 - Global - 120,400,000/2,700,000; USA - 29,400,000/534,100 Testified before the House Energy and Commerce Oversight & Investigations Subcommittee chaired by Diana De Gette (D-CO) with ranking member Morgan Griffith (R- VA). Good hearing with the usual snarkiness from David McKinley (R-WV) and Gary Palmer (R-AL). Several question centered around the GOP angry because the Dems are not giving Trump enough credit for the vaccine. It is reflecting what Trump has been saying to the media. Pres. Joe Biden sent me a thank you letter: Letter from president Joe Biden PRESS: NBC Late Show with Seth Meyers; White House Press Conference