March 1, 2021 at 8:38 p.m. EST

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1. 2021-02-27 00:00 Anthony S. Fauci open
   February 27, 2021 - Global - 113,200,000/2,500,000; USA - 28,300,000/509,000 Had good conversation with Ashish Jha. He is a good guy and he wants to understand much better why I am insisting on a single dose of the vaccine rather than adhering to what others are suggesting about giving all one doses and then worrying about the second dose three months later in order to protect as many vulnerable people as one can. I explained to him our strategy that the major concern is the evolution of mutations (variants) that would not be covered by a less than optimal level of neutralizing antibody. We know that when we look at the in vitro data the variants diminish the efficacy of the vaccine-induced antibodies; however, the high levels of antibodies induced by the 2nd dose give some degree of protection (cushion) even against the mutants. Therefore. we are concerned that if we only give first doses and we wait three months or more to give the second dose that variants may dominate and infect the suboptimally protected people. In addition, a suboptimum level of response could actually select for mutants. In addition, there was no reason why we cannot dramatically increase the administration of doses together with the markedly increased availability of vaccine such that we can have our cake and eat it, namely, we can give a lot more first doses at the same time as we keep up with the second doses. We really need the CDC or another organization to model that. I will explain this all to Ron Klain on Sunday. I had an important conversation today led by Janet Woodcock and Peter Marks of the FDA about the J & J EUA. Also on the call were Francis Collins, Cliff Lane, and Rochelle Walensky.The subject matter was that their advisory committee (VRBAP) for consideration for an EUA for the J & J product (Ad26). The committee unanimously and strongly recommended an unqualified EUA even though the data for elderly individuals older than 60 years old with comorbidities was 42%. However, there were not enough data points to be able to make a definitive statement that there is a significant diminution of efficacy in that subgroup. Janet and Peter are very concerned since they wanted the recommendation to be that the EUA would involve people younger than 60 years old. Apparently, the AC IP will go along with that recommendation. Rochelle and I in our conversation with Jeff Zients had decided that when asked by the press we would say that this is an excellent vaccine equivalent to the other two. It might become problematic if the press focuses on that group older than 60 years old with comorbidities. The fact is that the numbers are so low that you cannot say anything about the subgroup analysis. Janet and Peter will face the press tonight. We help them to get a consistent message with ours. This is critical since I will be on four of the Sunday talk shows tomorrow. Throughout the late afternoon I was on several calls with Jeff Z who kept on checking with Ron Klain regarding what the right approach would be when asked on TV about what people who had both doses of vaccine could do with each other such as having a dinner with )00; USA - 28,400,000/5 10,800 the shows and said that I was fabulous. family and a few guests all of whom were vaccinated. Ron was quite concerned that I not go too far out on a limb and say that vaccinated people can safely interact with unvaccinated people in a household setting. Ron was also concerned about the issue a vaccinated people interacting with unvaccinated children. Finally after many calls going back and forth between me and Jeff and then between Jeff and Ron and back to me again we decided to have a 3 way call among Jeff, Ron, and me. We worked it out such that I will say that I am comfortable with adults in a small gathering within the home not wearing masks as long as everyone was vaccinated. Importantly, I would stay that the CDC would be coming out with recommendations in the next couple of weeks. PRESS: On Saturday Night Live played by Kate McKinnon: Pop Culture SNL dreams up a Fauci-hosted game show where contestants vie for the vaccine Travis M. Andrews
2. 2021-02-28 00:00 Anthony S. Fauci open
   Feb. 28, 2021 at 12:51 a.m. EST
3. 2021-02-28 00:00 Anthony S. Fauci open
   February 28, 2021 (Sunday) - Global - 113,500,000/2,500,000; USA - 28,400,000/510,800 Big topic on the Sunday shows (see below) was the EUA Issued by the FDA for the Johnson and Johnson adeno virus vaccine. Also, there is concern that I expressed about easing up on prevention modalities since the decreasing slope up infections is starting to show signs of plateauing. On Face the Nation( see below) Margaret Brennan showed a clip of me being portrayed on Saturday Night Live by Kate McKinnon. Also, the governor of South Dakota Kristi Noem said that I was almost always wrong. She claims that the most important parameter of how well you are doing is how you maintain hospital capacity. When Margaret play that clip I was kind to the governor by saying different states do different things and in different ways, whereas I might have pointed out that her state has the most deaths per capita by COVID-19 than any other state in the country. Got a call from Jeff that Anita Dunn saw me on all the shows and said that I was fabulous. Flattening of decline concerning. We shall see what happens in the coming days and weeks. NATIONWIDE COVID-19 METRICS. 7-DAY AVERAGE LINES Apr 1- Feb 286 Daily Tests Feb 28: 1,346,785 7-Day Avg: 1,487,999 Feb 28: 54,288 Daily Cases 7-Day Avg: 67,114 Currently Hospitalized 7-Day Avg: 52,083 Feb 28: 47,352 Daily Deaths Feb 28: 1,049 7-Day Avg: 1,895 2.3M 2.2M 2.1M 2.0M 1.9M 1.8M 1.7M 1.6M 1.5M 1.3M 1.2M 1.1M 1.0M 0.9M 0.8M 0.7M 0.6M 0.5M 0.4M 0.3M 0.2M 0.1M Apr Jul Oct Jan1 325,000 300,000 275,000 250,000 225,000 200,000 175,000 160,000 125,000 100,000 75,000 50,000 25,000 ie) Apri Jul Oct Jan1 130,000 120,000 110,000 100,000 90,000 80,000 70,000 60,000 50,000 40,000 30,000 20,000 10,000 ie) Apri Jul Oct Jan1 4,500 4,000 3,500 3,000 2,500 2,000 Apri Jul Oct 1 Jan Source: The COVID Tracking Project Confirmed Cases {Thousareds) ayia ASL 4/26 New Daily Confirmed COVID-19 Cases in the U.S. Tila 7fL9 as? ais B16 aya 3/13 Sy20 2020/2021 ae WLLL 1k 11/8 Vis LaG 1a @Single-day Record ) ralz? Liz ilo afi? 1/24 ar a9.3 ayia aad Had zoom call today with Ron Klain arranged by Jeff an included me Bechara, Marcela, Rochelle, Natalie, and others. The main topic was whether we should stick with our strategy of two doses in the usual time frame or switch to one dose and extend the interval by a couple of months before giving the second dose. Ron is concerned that in November we will be criticized for having let a few million people who would have been vaccinated remain UN vaccinated This Week with George Stephanopoulos; CNN 'the Nation '5400,000/5 12,000 ',900,000/5 13,100 because we wanted to give two doses to everyone. I was the main explainer emphasizing that the second dose gives a much higher titer of antibody that will address at least partially the inevitable evolution of variants including those from California and importantly the B.1.526. Ron did not want to tell us what to do but he wanted to make sure that we seriously considered both alternatives and were comfortable without decision to stick with two doses on the regular regiment. The ACIP recommended to CDC to implement the EUA for the J & J vaccine. Now the CDC needs to recommend the distribution and we can start distributing 4,000,000 doses almost immediately and then we will have 20 million by the end of March and a total of 100,000,000 by the end of June PRESS: Was on 4 Sunday talk shows: ABC This Week with George Stephanopoulos; CNN State of the Union with Dana Bash; CBS Face the Nation with Margaret Brennan; NBC Meet the Press with Chuck Todd.
4. 2021-03-01 00:00 Anthony S. Fauci open
   March 1, 2021 - Global - 113,800,000/2,500,000; USA - 28,400,000/512,000 • We did our weekly briefing of Principals - Cabinet members and deputies • Did a podcast with the New Jersey Council of Churches PRESS: NPR Radio 1A; Podcast with Kai Kuperschmidt (Science Magazine) on HIV versus COVID-19 vaccines; White House Press Conference (Routine 3x/week);Satellite Radio Tour for Native Americans; Podcast with the Interactive Advertising Bureau (David Cohen);
5. 2021-03-01 00:00 Anthony S. Fauci
   March 1, 2021 at 8:38 p.m. EST
6. 2021-03-01 00:00 Anthony S. Fauci open
   Mar 1, 2021
7. 2021-03-02 00:00 Anthony S. Fauci open
   March 2, 2021 - Global - 114,100,000/2,500,000; USA - 28,500,000/513,100 Still coming down, but the slope is changing: New Daily Confirmed COVID-19 Cases in the U.S. a og Bare Tee YE tit TEE prt LTT Oye fides OZT E120 Lia BEFLT Pirie STALL BYTE TCT Sz/OC BTAOE TTS boc ants oné EVG Des ene oVe one aie eve Sit aes pis bers evs os a5 ome ol mir Sie Gre reve SWE 2020/2021 Participated in the University of Edinburgh "Futures Conversations" Chaired by Professor Peter Mathieson (Vice-Chancellor, University of Edinburgh) and involving a conversation between me and Professor Nanshan Zhong (China) and Sheila Tlou (former Minister of Health of Botswana) on the global impact of COVID-19. We spoke about global solidarity for vaccine equity. Also, spoke about the variants. Also, spoke about the approach that China took with the outbreak, i.e. complete lockdown Call from Larry Horowitz. Nancy Pelosi is angry about the fact that J & J is being equated with the mRNA vaccines since she has seen the data about the people >60 yo with co-morbidities. Also, she does not like the 72% versus 94-95% for mRNA. She is taking her annoyance out on the medical team (she has not The Vaccination Progress Report 7-day average daily doses administered by week as of 2/28/2021 DOSES PER DAY 2,000,000 1,800,000 1.7TMM/ DAY 1.7MTM / DAY 1,600,000 1.5TM / DAY 1,400,000 w, aay 1.3M / DAY 1,200,000 imM/ 1,000,000 1.4M / DAY 0.9 M / DAY 800,000 600,000 400,000 200,000 oO JANUARY JANUARY JANUARY 27- FEBRUARY FEBRUARY FEBRUARY FEBRUARY 13-19 20-26 FEBRUARY 2 3-9 10-16 17-23 22-28 ost (see below) ',900,000/5 15,300 PRESS: Podcast with Kai Kuperschmdt (follow-up from yesterday0; Seattle Gay News interview; Interview for Pritzer Forum/Chicago Council; Hispanicize PSA taping (Paola Ramos); Telemundo 52 Los Angeles; In Washington Post (see below) Fauci: U.S. must stick with two-shot strategy for Pfizer-BioNTech, Moderna vaccines Delaying a second dose to inoculate more Americans creates risks, infectious-disease expert says By Dan Diamond
8. 2021-03-02 00:00 Anthony S. Fauci open
   Mar 2, 2021 Source: Johns Hopkins University CSSE COVID-19 Data - Last updated 3 March, 10:03 (London time) CC BY ig and Note that Europe cases are going up. They are using the 1 dose of vaccine approach: Governors of Texas and Mississippi withdraw all public health measures such as masking and not doing indoor dining. I and Rochelle and Biden on TV saying that this is risky and illadvised. COVID-19 Vaccinations in the United States Overall US COVID-19 Vaccine I Deliveries and Administration; Maps, charts, and data provided by the CDC, updated daily by 8 pm ett Represents all vaccine partners including jurisdictional partner clinics, retail pharmacies, long-term care facilities, Federal Emergency Management Agency and Health Resources and Services Administration partner sites, and federal entity facilities. People Vaccinated Receiving 1 or More Doses Receiving 2 Doses Total Vaccine Doses Total 51,755,447 26,162,122 Delivered 102,353,940 % of Total Population 15.6% 7.9% Adieunicerea 78,631,601 Population 2 18 Years of Age 51,708,435 26,144,667 % of Population > 18 Years of Age 20.3% 10.2% Learn more about the distribution of vaccines. Read more about how these data are reported. CDC I Data as of: Mar 02 2021 6:00am ET I Postec: Mar 2 2021 12:26PM ET _ THE LAST THING 8EFORE WE GO DR. FAUCI'S EERILY ACCURATE PREDICTION PRESS: BBC Scotland Morning Radio Show; Black News Channel with Kelly Wright; Brandeis Webinar with Atul Gawande and Elizabeth Rosenthal; Town Hall with United Food and Commercial Worker Union; CNN with Erin Burnett; My prediction, one year ago on NBC reported here by brian Williams: One year ago, Fauci predicted how bad a Covid pandemic could be In March 2020, Dr. Anthony Fauci spoke with NBC News Chief Foreign Correspondent Richard Engel before Covid-19 became a global pandemic. MSNBC's Brian Williams shares how shockingly accurate Fauci's predicted ended up being. ,600,000/5 17,200 New Daily Confirmed COVID-19 Cases In the U.S. a0 AEE Tie PIT tit TEE bt LTT owe E/T fides OZT ELT Bestt ZEEE STIL BYEt TET Sz/OC TTS ants one oye Ga aif one Big eye ot Bes THs Pra one ol mir ait tas SWE 2020/2021
9. 2021-03-03 00:00 Anthony S. Fauci open
   March 3, 2021 - Global - 114,400,000/2,500,000; USA - 28,500,000/515,300 Still plateauing: New Daily Confirmed COVID-19 Cases In the U.S. a0 i 230 z:: z > 2 q fal i E &§ 'al too o Re Re Re I a ok i a aes BR ia BER THERE PTR RRR PRR ES OP RE Ew SS TS EP SSSR RES SSR SR GE TERE ER NRG SR 2020y 2021 Daily new confirmed COVID-19 cases per million people er Shown is the rolling 7-day average. The number of confirmed cases is lower than the number of actual cases; the main reason for that is limited testing. Cunear I tos Europe South America ---- North America Asia I --- Africa - ~ Australia an 1, 2020 Apr 30 Aug 8 Nov 16

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