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Okay. I just want to make sure that we get to everything. Early in 2020, did you ever have any concerns about the safety of SARS-CoV-2 vaccines that were being developed?
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So coronavirus vaccines induce Th2 immune DC.Scheduling@LexitasLegal.com pathology using killed vaccines plus alum. So I talked at a WHO meeting early on in the pandemic to say that alumbased vaccines, which have a tendency to -- I probably need to explain what a Th2 immune response is.
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We don't really have to. We'll look it up.
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Okay. So basically there's a massive inflammatory response that has the potential to be lifethreatening, and the SARS coronavirus vaccines, from 2003, that the NIH had purchased, were both adjuvanted with alum. And we published papers showing that that drives a strong Th2 immune response. So my concern, and I expressed this to the WHO and to other groups, was that we needed to look carefully for vaccine-induced immune pathology. Ultimately, we published a paper with the VRC. That was one of the experiments we set up to do, where we took mRNA vaccines and we took killed vaccine preparations with alum and compared them head-to-head for the ability to induced Th2 responses. The mRNA vaccines did not cause it. The recombinant protein, or the killed vaccines plus alum caused a big Th2 response. Now, the Chinese vaccines were killed vaccines with alum, which I think was inappropriate. The mRNA vaccines, though, were tested for that using homologous virus challenge. DC.Scheduling@LexitasLegal.com
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2026-04-10 09:00
Christina Salazar
Okay. So at this point --
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At that point, the downstream question is whether if you have significant amounts of virus variation and you're infecting the original Wuhan mRNA vaccine, will breakthrough infection induce an immune pathology phenotype, and those are the kinds of things we're interested in studying now.
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Okay. Let's see. William had a followup question, so I'll let you do that one.
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Back to the February 1st call, you said that you did not recall and could not figure out how you got added to that call. Was there any suggestion or implication or direction to you not to speak up on that call?
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So again, I'm kind of surprised that they didn't know I was there.