Private channel session 714

7 messages over 1h 9m, 2020-12-22 – 2020-12-22.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

2020-12-22 14:12 Robert F. Garry open PDF p.339

@Kristian Andersen D614G and N501Y may be enough?
2020-12-22 14:14 Robert F. Garry open PDF p.339

N417K
2020-12-22 14:18 Robert F. Garry open PDF p.340

@Kristian Andersen And since you corrected me -thx - the N417K could contribute to enhanced receptor binding. K binding better to D.
2020-12-22 14:18 Robert F. Garry open PDF p.340

Actually it is K417N - so not likely to help with receptor binding.
2020-12-22 14:40 Robert F. Garry open PDF p.340

@Kristian Andersen Wait - take the beer back it is actually K417N.
2020-12-22 14:44 Robert F. Garry open PDF p.340

shared file(s): image.png
2020-12-22 15:21 Robert F. Garry open PDF p.340

@Kristian Andersen Here making a big deal about K417 salt bridge to D30: https://www.pnas.org/content/117/25/13967