--- type: Conversation title: Private channel session 876 description: "slack conversation, 36 messages, 2021-01-26." tags: - conversation - slack medium: slack message_count: 36 started_at: "2021-01-26T07:04:36" ended_at: "2021-01-26T11:11:12" duration_seconds: 14796 sources: - { id: slack_pm, resource: /sources/slack-pm.md, title: Slack / Private Message Drop, author: "process:senate-hsgac-release" } generated: { by: randpaul-corpus-pipeline/1.0, at: "2026-08-01T12:42:27Z" } status: stable --- A slack conversation of 36 messages spanning 4h 6m. # Metadata - **Started:** 2021-01-26T07:04:36 - **Ended:** 2021-01-26T11:11:12 - **Duration:** 4h 6m - **Participants:** 3 - **Source:** [slack_pm](/sources/slack-pm.md) - **Pages:** 452-455 # Participants * [Andrew Rambaut](/people/andrew-rambaut.md) * [Edward C. Holmes](/people/edward-c-holmes.md) * [Kristian G. Andersen](/people/kristian-g-andersen.md) * [Robert F. Garry](/people/robert-f-garry.md) # Transcript **[2021-01-26T07:04:36] Kristian G. Andersen:** Yeah, saw parts of it - so dumb. **[2021-01-26T07:05:28] Kristian G. Andersen:** Separately - I think they might want to look up GOF in a dictionary... **[2021-01-26T07:10:31] Robert F. Garry:** At least the gorilla is doing OK even thou infected with ~LucifeR~ "LesteR." Or pick your own name LenoiR, LuthoRalso possibilities. **[2021-01-26T07:37:57] Kristian G. Andersen:** Yeah, we might need to find a name for that one - last sequencing run, ~50% LesteR.... **[2021-01-26T07:38:20] Kristian G. Andersen:** I suspect Lester and Nelly will have to battle it out - should be interesting. **[2021-01-26T07:38:27] Robert F. Garry:** @Andrew Rambaut is the go to for names... **[2021-01-26T07:45:05] Kristian G. Andersen:** Google Scholar is now indexing Virological... :wink: [shared file(s): Screen Shot 2021-01-26 at 7.44.40 AM.png] **[2021-01-26T07:46:48] Andrew Rambaut:** Enjoy - all 191 pages of it... [shared file(s): 2021-01-26_SQuay_Bayesian Analysis of SARS-CoV-2.pdf] **[2021-01-26T07:47:12] Andrew Rambaut:** How do these people have so much time on their hands? **[2021-01-26T07:47:28] Kristian G. Andersen:** Just saw it... I have no idea - I guess it's all they do? **[2021-01-26T07:47:41] Andrew Rambaut:** I like the pacman logo though **[2021-01-26T07:50:06] Kristian G. Andersen:** I should point out that Trevor was / is working on a Bayesian framework for this as well. Picking priors is a littlesketchy... **[2021-01-26T07:50:57] Andrew Rambaut:** We should reply to tell him that. Perhaps they could collaborate **[2021-01-26T07:54:39] Kristian G. Andersen:** That'd be fun! I do have _some_ respect for Quay though - he noticed the early ENA samples - still not explained. **[2021-01-26T08:11:40] Andrew Rambaut:** Cambodian bat genomes - just the variable loop: [shared file(s): image.png] **[2021-01-26T08:11:58] Andrew Rambaut:** Rooted by other pangolins **[2021-01-26T08:12:58] Kristian G. Andersen:** Just a matter of time before we see a near-perfect match to the RBD in bats, **[2021-01-26T08:15:28] Robert F. Garry:** Here's that nucleotide alignment of spike at 30,000 feet - from the ATG to the FCS- not the mess I thought it wouldbe - you can clearly see the indels. To Kristian's point - the RBD actually aligns pretty well. [shared file(s): image.png] **[2021-01-26T08:23:36] Robert F. Garry:** And a bit of S2 - highly conserved at the amino acid level - but you can clearly see many instances of the ** ** **pattern, with the mismatches being the "wobble" base in the triplet. Designed by nature not a supervillain. [shared file(s): image.png] **[2021-01-26T08:48:18] Andrew Rambaut:** Cara is trying again to get me to come to China: [shared file(s): image.png] **[2021-01-26T08:48:35] Andrew Rambaut:** This time she has a name for the organisation. **[2021-01-26T08:49:08] Andrew Rambaut:** If you look up "North American Foundation for Science and Technology" you get this very convincing website: https://www.northamericanfoundationforscienceandtechnology.com **[2021-01-26T08:50:35] Andrew Rambaut:** https://www.northamericanfoundationforscienceandtechnology.com/our-team **[2021-01-26T08:51:17] Andrew Rambaut:** shared file(s): image.png **[2021-01-26T09:11:26] Robert F. Garry:** Weed and stem cells - seems like a natural to me. Cara seems nice too, but might just be a bit of a trap... **[2021-01-26T09:16:22] Andrew Rambaut:** A trap? Surely not: ` **[2021-01-26T09:30:09] Kristian G. Andersen:** Love the URL - a little hard to memorize, but still. Stellar. **[2021-01-26T09:36:08] Kristian G. Andersen:** Address linked to Exosomecure Research Foundation too - I suspect Johnny's home address. Nice area. **[2021-01-26T10:25:51] Robert F. Garry:** So, the real question arises. In one case - Andrew's email - Cara is Cara Li. But on the website the Cara is CaraDong. More than one Cara? Cara got married and changed her name? **[2021-01-26T10:26:35] Robert F. Garry:** I think this may be a job for Alina or DRASTIC... **[2021-01-26T10:31:01] Kristian G. Andersen:** OMG the inconsistencies! Clearly came from the lab. **[2021-01-26T10:46:14] Robert F. Garry:** MW251308 to MW251312 **[2021-01-26T10:47:02] Robert F. Garry:** Yuri has moved up to clustal W - however the Thai bat viruses are interesting [shared file(s): image.png] **[2021-01-26T10:54:16] Kristian G. Andersen:** Their obsession with the FCS will backfire - we'll get viruses with more similar insertions and then their main argument becomes completely mute. Of course, they'll just move the goal post. **[2021-01-26T10:57:38] Robert F. Garry:** RmYN02 like cleavage site [shared file(s): image.png] **[2021-01-26T11:11:12] Robert F. Garry:** MW251308 this is Linfa and apparently he has some Thai pangos as well..... [shared file(s): image.png]