--- type: Conversation title: support on ebola description: "email conversation, 15 messages, 2014-08-07." tags: - conversation - email medium: email message_count: 15 started_at: "2014-08-07T19:17:00" ended_at: "2014-08-08T09:15:00" duration_seconds: 50280 sources: - { id: gates, resource: /sources/gates.md, title: Gates Package, author: "process:senate-hsgac-release", last_modified: 2026-07-31 } generated: { by: randpaul-corpus-pipeline/1.0, at: "2026-08-01T12:42:27Z" } status: stable --- A email conversation of 15 messages spanning 13h 58m. # Metadata - **Started:** 2014-08-07T19:17:00 - **Ended:** 2014-08-08T09:15:00 - **Duration:** 13h 58m - **Participants:** 6 - **Source:** [gates](/sources/gates.md) - **Pages:** 74-81 # Participants * [Anthony S. Fauci](/people/anthony-s-fauci.md) * [Francis S. Collins](/people/francis-s-collins.md) * [John Mascola](/people/john-mascola.md) * [Richard Koup](/people/richard-koup.md) # Transcript **[2014-08-07T19:17:00] unknown:** gatesfoundation.org] Dear Francis and Tony, It is clear that the problem, concern and media attention surrounding the treatment of the two individuals now in Atlanta add further weight to the Ebola outbreak concerns, which we have discussed by email over the past week or so. Although the overall burden of disease due to Ebola is not of the magnitude of the conditions we address strategically, we recognize that the current situation calls for action and places considerable pressure on your agency and WHO and others of our key partners. For these reasons we have provided emergency funds to WHO and UNICEF to support public health measures as well as on the ground human resources in the target… **[2014-08-07T19:37:00] Anthony S. Fauci:** We should discuss how we are going to respond to Trevor From: Trevor Mundel [mailto NO gatesfoundation.org] Sent: Thursday, August 07, 2014 7:17 PM To: Collins, Francis (NIH/OD) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: Support on Ebola Dear Francis and Tony, It is clear that the problem, concern and media attention surrounding the treatment of the two individuals now in Atlanta add further weight to the Ebola outbreak concerns, which we have discussed by email over the past week or so. Although the overall burden of disease due to Ebola is not of the magnitude of the conditions we address strategically, we recognize that the current situation calls for action and places considerable… **[2014-08-07T19:37:00] Anthony S. Fauci:** We should discuss how we are going to respond to Trevor **[2014-08-07T19:37:00] Anthony S. Fauci:** We should discuss how we are going to respond to Trevor From: Trevor Mundel [mailto gatesfoundation.org] Sent: Thursday, August 07, 2014 7:17 PM To: Collins, Francis (NIH/OD) [E]; Fauci, Anthony (NIH/NIAID) [E] Subject: Support on Ebola Dear Francis and Tony, It is clear that the problem, concern and media attention surrounding the treatment of the two individuals now in Atlanta add further weight to the Ebola outbreak concerns, which we have discussed by email over the past week or so. Although the overall burden of disease due to Ebola is not of the magnitude of the conditions we address strategically, we recognize that the current situation calls for action and places considerable… **[2014-08-07T21:20:00] Francis S. Collins:** I was thinking exactly the same thing. Do you see ways that BMGF could be helpful? FC **[2014-08-07T21:20:00] Francis S. Collins:** I was thinking exactly the same thing. Do you see ways that BMGF could be helpful? FC **[2014-08-07T21:20:00] Francis S. Collins:** I was thinking exactly the same thing. Do you see ways that BMGF could be helpful? FC **[2014-08-07T21:49:00] Anthony S. Fauci:** I have allocated enough money to do the VRC vaccine trial and so we do not need Gates money. I believe that BARDA has enough money to accelerate the zMapp production. I will give John Mascola a call and find out if he can think of any way that Gates can help with his trial. **[2014-08-07T21:49:00] Anthony S. Fauci:** I have allocated enough money to do the VRC vaccine trial and so we do not need Gates money. I believe that BARDA has enough money to accelerate the zMapp production. I will give John Mascola a call and find out if he can think of any way that Gates can help with his trial. **[2014-08-07T21:49:00] Anthony S. Fauci:** I have allocated enough money to do the VRC vaccine trial and so we do not need Gates money. I believe that BARDA has enough money to accelerate the zMapp production. I will give John Mascola a call and find out if he can think of any way that Gates can help with his trial. **[2014-08-08T08:49:00] John Mascola:** Tony, Several relevant items. 1. We heard from GSK that Welcome trust is willing to help support expanded international trials and this is being pursued. Rip Ballou of GSK is coordinating with Rick Koup. 2. We discussed with Nelson Michael and colleagues yesterday, a trial in Uganda that would be run by African investigators and generate data in African volunteers. Some funding to support this may be helpful., but there may be existing NIAID/DoD funds existing to support this. There are many moving parts here and several fairly imminent decisions. Rick has been on all the calls with BARDA, GSK, WHO etc. A first key step in to find out what BARDA plans to do, and based on that, decide if… **[2014-08-08T08:49:00] John Mascola:** Tony, Several relevant items. 1. We heard from GSK that Welcome trust is willing to help support expanded international trials and this is being pursued. Rip Ballou of GSK is coordinating with Rick Koup. 2. We discussed with Nelson Michael and colleagues yesterday, a trial in Uganda that would be run by African investigators and generate data in African volunteers. Some funding to support this may be helpful., but there may be existing NIAID/DoD funds existing to support this. 3. GSK is close to final decision about making larger lot of vaccine. BARDA or Gates funding could play a role here. There are many moving parts here and several fairly imminent decisions. Rick has been on all the… **[2014-08-08T08:56:24] Anthony S. Fauci:** Inline-Images: image001.png Francis: I will forward to you in another e-mail the response of John Mascola when I asked him if Gates could help. Stay tuned. Tony **[2014-08-08T08:57:08] Anthony S. Fauci:** Inline-Images: image001.png As per my prior e-mail. **[2014-08-08T09:15:00] Richard Koup:** John and Tony: Here is the latest I know. We have been getting a lot of additional clarifying questions from BARDA subsequent to our telecom, so I am fairly confident they will fund production of 1 "lot" of vaccine, but I remain unclear as to when we will hear definitively. Wellcome Trust seems willing to provide half the funds for another lot, but only if GSK or some other source partners for the other half of the funds. GSK leadership is not interested, but Rip Ballou is checking with MRC and others to see what can be done. WHO is anxious to start additional small phase 1 trials in Africa (20 subjects per country, at MRC sites). We currently have adequate vaccine stock for our NIH-based…